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AI-Powered IOL Customisation: How Artificial Intelligence Is Improving Cataract Outcomes

Oct 20, 2025

If you’ve been following developments in cataract surgery, you’ll know that technology is moving at an incredible pace. What was once a straightforward operation to replace a cloudy lens has become an arena of high-tech precision, where every detail of your eye can be measured, modelled, and optimised. One of the most exciting developments in this space is the use of artificial intelligence (AI) to customise intraocular lenses (IOLs).

In the past, lens selection often relied on broad formulas and the surgeon’s skill in interpreting a patient’s eye measurements. While these methods worked well for most, some people ended up with small refractive errors – meaning they still needed glasses for certain tasks. AI has begun to change that. By analysing vast datasets of patient outcomes and eye measurements, AI systems can now predict the most suitable IOL for each eye with incredible accuracy.

This article will take you on a journey through the world of AI-powered IOL customisation. We’ll look at how AI tools are used in practice, the benefits they bring to patients and surgeons, and what the future could hold. You’ll see how algorithms aren’t replacing doctors, but instead helping them achieve outcomes that were once thought impossible.

Why Personalisation Matters in Cataract Surgery

When it comes to your vision, even the smallest detail makes a difference. Think about it – a fraction of a millimetre in lens placement or a slight miscalculation in lens power can mean the difference between crystal-clear sight and needing glasses for everyday activities.

Cataract surgery is already one of the most successful medical procedures in the world. But “success” has evolved. Decades ago, the goal was simply to restore basic sight. Today, patients expect much more. They want to read, drive, and use their devices without glasses, often at multiple distances. Meeting these expectations requires an extremely high level of precision in lens power calculation.

Traditional formulas – such as SRK/T, Hoffer Q, or Holladay – have served surgeons well for years. But they were built on linear models that couldn’t account for every variable. Eyes are complex, and factors like corneal shape, anterior chamber depth, and lens thickness interact in ways that are difficult to capture with simple equations. This is where AI comes in.

By learning from thousands, even millions, of previous cases, AI systems can spot patterns no human could. They can tell surgeons not just what lens power might work, but what is most likely to give that individual patient the outcome they’re hoping for.

The Role of Biometric Data

At the heart of IOL customisation is biometric data – the measurements of your eye that feed into calculations. Modern biometers measure axial length, corneal curvature, anterior chamber depth, and lens thickness. Some even map the corneal surface in high detail, giving a three-dimensional picture of the eye’s refractive system.

On their own, these measurements are powerful but incomplete. Two patients with the same axial length might still need different lenses because of differences in corneal shape or lens position. AI can process these nuances. By looking at not just one variable but the relationships between all of them, AI can refine predictions to a level never seen before.

For example, AI might learn that a particular corneal curvature interacts with lens thickness in a way that slightly shifts the effective lens position post-surgery. While traditional formulas might miss this, the AI system captures it, leading to a more precise recommendation.

How AI Predicts the Best IOL Power

So, how exactly does AI help? Let’s break it down.

  1. Data collection – AI systems are trained on large databases of past cataract surgeries. These include preoperative measurements, the type of IOL implanted, and postoperative outcomes.
  2. Pattern recognition – The AI looks for patterns in how biometric factors relate to surgical outcomes. It learns, for instance, that in eyes of a certain length and curvature, the standard formula tends to underpredict lens power.
  3. Prediction – When new patient data is entered, the AI system doesn’t just apply a formula. Instead, it runs the data through its trained model, which outputs a personalised prediction of the IOL power likely to give the best visual result.
  4. Continuous learning – Many AI systems are designed to keep learning. Every new surgery adds to the database, refining the accuracy of predictions over time.

The result? Patients are less likely to experience refractive surprises – those moments when, after surgery, their vision isn’t quite what they hoped. Instead, they get a result closer to perfect focus.

AI in Toric and Premium Lens Planning

Customisation becomes even more important when we’re dealing with premium IOLs such as toric, multifocal, or extended depth of focus (EDOF) lenses. These lenses are designed not just to remove cataracts but to correct astigmatism or provide vision at multiple distances.

For toric lenses, alignment is critical. Even a small rotational error can reduce their effectiveness. AI can simulate how a toric lens will perform in a given eye, helping surgeons choose the exact power and alignment that will maximise clarity.

For multifocal and EDOF lenses, AI can model likely patient satisfaction by considering lifestyle factors, pupil size, and even how much tolerance a person might have for visual phenomena like halos. In this way, AI goes beyond pure optics and begins to consider the “human factors” that influence whether a patient is truly happy with their outcome.

Simulating Visual Outcomes Before Surgery

Imagine being able to “see” your likely post-surgery vision before the operation. AI is bringing us closer to that reality. By combining biometric data with advanced modelling, AI can generate simulations of how a patient will view the world through different types of lenses.

This can be a game-changer for informed consent. Instead of simply explaining the pros and cons of various IOLs, surgeons can show patients realistic previews. For example, someone considering a multifocal lens could see a simulated night-time street scene with halo effects, compared to the sharper single-focus vision of a monofocal lens.

This level of personalisation empowers patients to make choices that align with their lifestyle and tolerance levels, reducing the risk of disappointment later.

Reducing Human Error in Calculations

Even the best surgeons are human, and humans can make mistakes. Data entry errors, misinterpretation of formulas, or inconsistencies between different measurement devices can all lead to small but important inaccuracies.

AI systems help mitigate this risk. Many platforms automatically check data consistency, flagging outliers or unusual combinations. They can cross-reference different biometric readings to ensure accuracy before final calculations are made.

By serving as an intelligent assistant, AI reduces the burden on surgeons, allowing them to focus on surgical technique and patient communication rather than worrying about calculation errors.

Customising IOL Design Through AI

Beyond selecting from existing lenses, AI is starting to influence how new IOLs are designed. Manufacturers are using AI-driven analysis of patient outcomes to refine lens geometry, material properties, and optical zones.

For example, AI might reveal that a certain lens design performs better in eyes with a particular corneal shape, prompting manufacturers to create variants tailored to those eyes. In the future, we may even see “made-to-order” IOLs produced for individual patients, with AI guiding every aspect of their design.

This represents a true shift towards personalised medicine, where your lens is not just chosen for you but actually designed with your unique eye in mind.

The Role of AI in Complex Cases

Not all cataract patients present straightforward cases. Some have had previous refractive surgery, such as LASIK or PRK, which alters corneal measurements. Others may have unusual eye anatomy due to conditions like keratoconus or very high myopia.

These are the cases where traditional formulas often fall short. AI, however, thrives on complexity. By training on data from similar “outlier” patients, AI can provide more reliable predictions in situations where human judgement alone might struggle.

For example, calculating IOL power after LASIK has always been tricky because corneal shape is altered. AI systems trained on large numbers of post-LASIK eyes can predict lens power more accurately than traditional methods, offering hope to patients who previously faced higher risks of refractive surprises.

Improving Patient Satisfaction

Ultimately, what matters most is how patients feel after surgery. Do they have the freedom to live without glasses? Do they feel their vision matches what they were promised?

AI contributes directly to patient satisfaction by making outcomes more predictable. But it also plays a subtler role: by helping surgeons guide patients towards realistic expectations. If a simulation shows that a patient is unlikely to tolerate multifocal halos, they can choose a different lens upfront, avoiding post-operative regret.

This combination of technical precision and personalised counselling leads to happier patients – and happier patients are the true measure of success in modern cataract surgery.

Ethical and Practical Considerations

Of course, the rise of AI in medicine brings with it important ethical and practical questions. Who is responsible if an AI prediction turns out to be wrong – the software company, the surgeon, or both? How do we ensure that AI recommendations are transparent and explainable, rather than black boxes?

There are also questions of access. Will AI-powered planning tools be available only in well-funded private clinics, or will they make their way into public health systems? If AI truly improves outcomes, then fairness demands that everyone should benefit, not just those who can pay extra.

Regulatory bodies are beginning to tackle these questions, but the field is still evolving. What’s clear is that AI must be seen as a tool that supports, rather than replaces, the surgeon’s expertise.

The Future of AI in Cataract Surgery

Looking ahead, the possibilities are vast. AI may soon integrate with real-time intraoperative systems, adjusting surgical plans on the fly based on how the eye responds during surgery. We may see AI-driven robots assisting in lens implantation, guided by predictive algorithms that ensure perfect placement.

On the patient side, we may see apps that connect biometric scans with AI models, giving patients an instant preview of likely outcomes from different IOL choices. Surgeons could then review these simulations together with patients, making the decision process more collaborative than ever before.

Ultimately, the goal is clear: to make cataract surgery so precise and personalised that every patient feels they’ve been given the perfect lens for their eyes.

FAQ Section

1. What exactly is AI-powered IOL customisation?
AI-powered IOL customisation is the use of artificial intelligence software to process detailed eye measurements and compare them with vast datasets from thousands of previous cataract surgeries. Instead of relying on fixed mathematical formulas alone, the AI system “learns” from real-world outcomes and can suggest the best lens power, design, and alignment for your individual eyes. It’s essentially a way of making your cataract surgery more personal and data-driven, ensuring the lens you receive is matched as closely as possible to your visual needs.

2. How does AI improve the accuracy of cataract surgery?
Traditional IOL power calculations depend on formulas that work well for the average patient but can fall short in more unusual eyes. AI improves accuracy by recognising complex relationships between measurements like corneal curvature, lens thickness, and axial length. It takes these interdependent factors and predicts how the lens will sit and function after surgery. This means fewer “refractive surprises” – situations where patients expect perfect vision but end up with residual blur or the need for glasses.

3. Can AI help me avoid wearing glasses after surgery?
AI increases the likelihood that you’ll achieve your desired outcome, whether that’s clear distance vision or reduced dependence on glasses for near work. While not every patient can eliminate spectacles completely, AI reduces the margin of error in lens selection, which is often the reason people still need correction after surgery. For patients choosing premium lenses such as multifocal or EDOF lenses, this higher accuracy can make a real difference to whether they enjoy comfortable glasses-free vision across multiple distances.

4. Is AI only used for advanced or premium lenses?
AI supports lens selection for both standard and premium IOLs, but its benefits are most noticeable with premium designs. For example, with toric lenses that correct astigmatism, precise axis alignment is essential, and AI can predict how rotation or misalignment will affect outcomes. Similarly, for multifocal or accommodating lenses, AI can help determine which design best suits the eye’s anatomy and the patient’s lifestyle. Even for monofocal lenses, AI still reduces the risk of residual refractive error, meaning more patients get the sharp distance vision they hoped for.

5. Does AI replace the surgeon’s judgement?
No – AI does not replace the surgeon but complements their expertise. Surgeons still interpret the results, discuss the options with patients, and decide on the final plan. AI acts as an intelligent assistant, offering recommendations based on patterns it has learned from huge datasets. Surgeons then combine these insights with their understanding of surgical technique, patient preferences, and medical history. This partnership ensures that decision-making remains human-led but supported by powerful computational tools.

6. How does AI help with complicated cases?
Patients who have had previous laser vision correction (LASIK, PRK, or SMILE) often present difficulties because their corneal shape is no longer standard, making formula predictions less reliable. Similarly, eyes with conditions such as keratoconus or extremely long or short axial lengths can be challenging. AI can handle these situations more effectively because it draws on data from comparable “non-standard” eyes in its training set. Instead of forcing an unusual eye into a general formula, AI uses pattern recognition to produce a tailored prediction, giving patients with complex cases greater confidence in their results.

7. Is this technology widely available right now?
AI-assisted IOL planning tools are currently more common in private eye hospitals and specialist clinics, though they are gradually being adopted more broadly. Like many new technologies, access often begins in centres with higher resources before filtering into wider healthcare systems. That said, as evidence builds around improved patient satisfaction and reduced need for corrective enhancements, there is strong motivation for AI systems to become part of standard cataract care worldwide. Availability may also depend on the software chosen, as some systems integrate directly with biometers and surgical platforms.

8. Can AI show me what my vision will look like after surgery?
Yes, one of the most patient-friendly developments is the ability to preview vision using AI simulations. These tools use your measurements to generate images of how you might see the world with different lens types. For example, you could compare a multifocal lens that allows reading without glasses but may cause halos at night, versus a monofocal lens that provides crisp distance vision but requires spectacles for near tasks. By seeing these side-by-side, you can make a more informed decision that reflects your lifestyle and tolerance for visual trade-offs.

9. Are there any risks with using AI in cataract surgery?
The main risk lies not in AI itself but in how it’s used. AI models are only as good as the data they are trained on, and while they are highly accurate, they are not infallible. Surgeons must always review AI predictions in the context of the individual patient’s health and expectations. Another consideration is transparency: some AI systems function as “black boxes” where the exact reasoning isn’t visible, so surgeons need to be confident in the system’s reliability. When used appropriately, AI adds safety by reducing human error, but it should never replace clinical judgement.

10. What does the future look like for AI in cataract treatment?
Looking ahead, AI is expected to play an even greater role, not just in planning but during surgery itself. Systems may soon adjust surgical parameters in real time, fine-tune laser incisions based on intraoperative feedback, and even guide robotic implantation of lenses with perfect accuracy. Beyond surgery, AI could help design next-generation “smart IOLs” that adapt dynamically inside the eye, or even provide post-operative monitoring to detect early complications. The long-term vision is a seamless, personalised surgical journey where every stage – from diagnosis to lens design to aftercare – is optimised by artificial intelligence.

Final Thoughts

AI-powered IOL customisation is not science fiction – it’s happening right now in clinics around the world. For patients, it means sharper, more predictable vision and greater freedom from glasses. For surgeons, it means tools that enhance decision-making and reduce uncertainty. And for the field of ophthalmology, it marks the beginning of a new era where data and human expertise combine to achieve results that neither could reach alone.

Cataract surgery has always been about giving people back the gift of sight. With AI, that gift is becoming more precise, more personal, and more powerful than ever before. If you’re considering cataract surgery and want to explore the latest in personalised lens technology, our team at the London Cataract Centre can guide you through your options and help you make the best decision for your eyes.

References

  1. Li, T., 2022. “AI-powered effective lens position prediction improves the accuracy of intraocular lens power calculation.” British Journal of Ophthalmology, 106(9), pp.1222-1229. Available at: https://bjo.bmj.com/content/106/9/1222 [Accessed 19 Oct. 2025].
  2. Stopyra, W., 2024. “A review of intraocular lens power calculation formulas based on artificial intelligence.” Journal of Clinical Medicine, 13:498. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10816994/ [Accessed 19 Oct. 2025].
  3. Zheng, X. et al., 2025. “Network meta-analysis of intraocular lens power calculation formulas based on artificial intelligence in short eyes.” BMC Ophthalmology, 25, Article number: 225. Available at: https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12886-025-04066-z [Accessed 19 Oct. 2025].
  4. Jiang, X. et al., 2025. “Comparative evaluation of traditional and AI-based intraocular lens power calculation formulas in highly myopic eyes.” BMC Ophthalmology, 25, Article number: 507. Available at: https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12886-025-04365-5 [Accessed 19 Oct. 2025].
  5. Redden, L. D., 2025. “Intraocular Lens Power Calculation—Comparing Big Data, AI, and Traditional Methods.” American Journal of Ophthalmology, (online ahead of print). Available at: https://www.ajo.com/article/S0002-9394%2825%2900071-6/fulltext [Accessed 19 Oct. 2025].